What is Electrospraying?
Electrospray is also an electrohydrodynamic process but a variant of traditional electrospinning. Electrospraying is used to produce particles; generally, in the range of 100's of nm to the 10's of μm, although Spraybase® has also demonstrated the production of particles in the 10's of nm range. The basic difference between these two processes lies in the concentration of the solution and molecular weight of the polymer.
HOW TO FORM PARTICLES
In electrospray the concentration of the polymer solution is sufficiently low to destabilize the charged jet. This then breaks down into small spherical droplets that solidify between the emitter tip and being deposited on the collector. With electospraying the polymer solution does not experience the same severe drawing seen in electrospinning, also the formed film consists of small droplets instead of fibers. This technique is used in a broad range of applications including drug delivery, drug formulation, cell encapsulation and thin layer deposition.
The Spraybase® Electrospray Starter Kit contains all the components needed to make and visualise a repeatable Taylor cone electrospray in order to generate particles in the nano and micro range.
This system is ideal for those who are comfortable using the traditional method of the syringe pump while at the same time having the capability of the pressure over fluid system. Two collectors are also provided which are interchangeable for those wishing to create both fibers and particles. In addition if you purchase a co-axial emitter you can make core-shell encapsulated particles.
HOW TO ELECTROSPRAY WITH SPRAYBASE®?
To see further demonstrations using Spraybase please visit our videos section.
METHOD OF FLUID CONTROL
Spraybase® recommends our pressure driven fluid system to control the flow rate for your experiments due to the superior control over the conventional syringe pump.
- Zero dead volume therefore ideal for precious materials and small quantities.
- Superior control over the flow rate especially for low viscous solutions.
- A continuous flow unlike the syringe pump which would have a pulsatile effect from the mechanics of the motor.
- The pressure over fluid is ideal to ensure a reproducible and robust technology
- Particle Generation
- Controlled Release
- Drug Delivery
- Thin Layer Deposition
Application Note 1: Using Spraybase to Electrospray of PVP
|Sample of Polymers Electrosprayed In-House|
|BSA||Bovine Serum Albumin|
|PLGA||Poly Lactic-co-Glycolic Acid|
|PGS||Poly Glycerol Sebacate|
|PVA||Poly Vinyl Alcohol|